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Figure 1 | Experimental & Translational Stroke Medicine

Figure 1

From: COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke

Figure 1

rCBF does not differ between COU254-treated mice and controls after tMCAO. Determination of regional cerebral blood flow (rCBF) using Laser Doppler flowmetry before the occlusion of the middle cerebral artery (baseline), 10 min after the occlusion (ischemia) and again 10 min after the removal of the filament (reperfusion) in COU254-treated mice and vehicle-treated controls (n = 3/group). No significant differences in rCBF were observed between the two groups. 1-way ANOVA, Bonferroni post hoc test, ns = not significant.

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Experimental & Translational Stroke Medicine

ISSN: 2040-7378

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