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Figure 5 | Experimental & Translational Stroke Medicine

Figure 5

From: Intra-arterial administration of recombinant tissue-type plasminogen activator (rt-PA) causes more intracranial bleeding than does intravenous rt-PA in a transient rat middle cerebral artery occlusion model

Figure 5

Bleeding score. Rats were subjected to 6 hours MCAo followed by approximately 18 hours of reflow. Treatment with rt-PA began 1 minute before reflow. The values are the mean ± SEM (n = 5, 5, 7, 5, 5, 5, 5, respectively). * p < 0.05 compared to indicated groups (Kruskal-Wallis, Newman-Keuls). # p < 0.05 compared to 30 mg/kg rt-PA, IV (Kruskal-Wallis, Newman-Keuls).

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