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Table 4 Analysis of Covariance (ANCOVA)

From: Intra-arterial administration of recombinant tissue-type plasminogen activator (rt-PA) causes more intracranial bleeding than does intravenous rt-PA in a transient rat middle cerebral artery occlusion model

Dependent Variable

Independent Variable

p-Value

Bleeding Score

Dose

< 0.0001*

 

Route

< 0.0001*

Infarct Volume

Dose

0.1787

 

Route

0.2020

Modified Bederson Score

Dose

< 0.0001*

 

Route

0.0310*

  1. Rats were subject to 6 hours of MCAo and then treated with saline or rt-PA. The indicated dependent variables were analyzed in relation to the independent variables.