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Table 4 Analysis of Covariance (ANCOVA)

From: Intra-arterial administration of recombinant tissue-type plasminogen activator (rt-PA) causes more intracranial bleeding than does intravenous rt-PA in a transient rat middle cerebral artery occlusion model

Dependent Variable Independent Variable p-Value
Bleeding Score Dose < 0.0001*
  Route < 0.0001*
Infarct Volume Dose 0.1787
  Route 0.2020
Modified Bederson Score Dose < 0.0001*
  Route 0.0310*
  1. Rats were subject to 6 hours of MCAo and then treated with saline or rt-PA. The indicated dependent variables were analyzed in relation to the independent variables.