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Table 1 Chronic angiotensin II infusion (2000 ng/kg/min) induces hypertension via blood cell associated AT1aR.

From: Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension

Experimental group Mean arterial pressure
(mmHg)
Wild type mice (WT) - saline loaded (- saline)
(n = 9)
110.8 ± 1.8
WT - angiotensin II loaded (- Ang II)
(n = 10)
125.4 ± 4.9*
AT1aR knockout mice (AT1aR -/- ) - Ang II
(n = 6)
103.4 ± 4.0
WT bone marrow chimera mice reconstructed with WT bone marrow (WT→WT) - saline
(n = 7)
96.6 ± 2.0
WT→WT - Ang II
(n = 8)
115.1 ± 6.1
AT1aR -/- →WT - Ang II
(n = 6)
108.9 ± 3.2
  1. Data are presented as mean ± SE. * denotes P < 0.05 vs WT - saline, † denotes p < 0.05 relative to WT - Ang II, ‡ denotes P < 0.05 vs WT→WT - saline