Figure 4
From: Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke
Minocycline reduces brain tissue injury in males (A) and females (B). The infarct size of ischemic MCA territory was estimated as the percent volume of the total ischemic hemisphere. Regardless of treatment adult females had significantly smaller infarct volumes (both P < 0.0001, ***) than aged and OVX females who were not different than each other (P = 0.77). All data expressed as means ± SD.