Figure 3
Treatment-dependent representative samples of impaired vessels (A) at 5 hours displayed by confocal laser scanning micrographs (100× magnification; scale bar = 20 μm). Total paravasal leakage (B) of FITC-albumin on ischemic hemisphere considering background staining as detected on contra-lesional hemisphere and extra-/intravasal ratio (C), calculated by means on affected hemisphere. Sample size for leakage and ratio at 5 hours (control/NBO/HBO/tPA/HBO+tPA): 8/8/8/7/8, at 25 hours: 8/8/8/8/8. Bars: means, lines: standard errors, P-value: *<0.05, **<0.01.