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Table 1 Physiological parameters.

From: Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke

  Sham Control NBO HBO tPA HBO+tPA ANOVA
  mean ± SD mean ± SD mean ± SD mean ± SD mean ± SD mean ± SD F ( P )
Weight (g) 357.8 ± 10.9 324.1 ± 45.6 304.3 ± 26.2 296.9 ± 26.5 334.8 ± 36.6 317.0 ± 17.5 4.6 (**)†
Duration of surgery (minutes) 63.8 ± 9.1 74.5 ± 25.5 66.6 ± 18.2 71.0 ± 22.8 68.3 ± 14.7 58.1 ± 12.6 1.5 (n.s.)
Temperature (°C)        
   Initial 37.5 ± 0.4 37.5 ± 0.4 37.6 ± 0.5 37.7 ± 0.3 37.5 ± 0.3 37.6 ± 0.5 0.7 (n.s.)
   After catheter 37.6 ± 0.2 37.3 ± 0.3 37.2 ± 0.3 37.1 ± 0.4 37.2 ± 0.7 37.2 ± 0.4 0.9 (n.s.)
   After clot injection 37.5 ± 0.0 37.4 ± 0.2 37.3 ± 0.3 37.2 ± 0.3 37.3 ± 0.7 37.1 ± 0.6 1.1 (n.s.)
   End of surgery 37.6 ± 0.4 37.5 ± 0.3 37.2 ± 0.2 37.3 ± 0.3 37.4 ± 0.4 37.0 ± 0.5 3.6 (**)‡
   After therapy n/a n/a 36.8 ± 0.8 37.3 ± 0.7 37.2 ± 0.8 36.9 ± 0.8 1.7 (n.s.)
Mean arterial pressure (mmHg)        
   After catheter 75.7 ± 3.5 82.9 ± 6.5 78.1 ± 8.4 77.8 ± 8.4 74.4 ± 9.0 79.9 ± 8.2 2.2 (n.s.)
   After clot injection 72.5 ± 3.5 78.2 ± 6.3 73.3 ± 5.8 77.1 ± 9.0 72.4 ± 7.9 77.7 ± 11.8 1.5 (n.s.)
   End of surgery 62.0 ± 3.0 75.3 ± 8.3 74.8 ± 13.2 79.1 ± 11.7 71.4 ± 7.2 81.9 ± 12.6 3.0 (*)§
   After therapy n/a n/a 96.0 ± 15.5 86.9 ± 10.7 84.4 ± 12.9 86.9 ± 17.0 2.1 (n.s.)
Heart rate (per minute)        
   After catheter 206.7 ± 42.5 188.5 ± 17.5 189.3 ± 12.6 191.5 ± 21.8 197.0 ± 18.5 192.7 ± 26.9 0.7 (n.s.)
   After clot injection 220.0 ± 49.5 194.5 ± 12.0 187.9 ± 17.0 203.1 ± 27.7 192.4 ± 21.7 203.9 ± 23.2 1.8 (n.s.)
   End of surgery 220.0 ± 40.9 198.5 ± 12.3 200.6 ± 25.3 200.9 ± 22.2 192.8 ± 18.9 200.2 ± 19.0 1.0 (n.s.)
   After therapy n/a n/a 203.1 ± 13.3 194.5 ± 13.0 204.2 ± 18.0 212.2 ± 21.7 2.7 (n.s.)
PaO 2 (mmHg)        
   After catheter 97.4 ± 9.1 102.8 ± 13.7 104.2 ± 22.6 97.9 ± 14.5 98.6 ± 9.2 105.1 ± 12.9 0.7 (n.s.)
   End of surgery 105.3 ± 12.3 114.1 ± 29.5 118.6 ± 19.9 108.5 ± 18.3 107.6 ± 13.8 114.7 ± 14.5 0.8 (n.s.)
   After therapy n/a n/a 117.8 ± 23.9 118.4 ± 18.2 117.7 ± 13.6 149.8 ± 28.9 8.8 (***)II
Blood glucose (mmol/l)        
   After catheter 13.5 ± 1.7 10.5 ± 1.9 12.2 ± 2.3 11.8 ± 1.5 11.1 ± 2.5 11.4 ± 1.6 2.1 (n.s.)
   End of surgery 13.2 ± 1.5 10.4 ± 1.9 11.8 ± 3.3 10.6 ± 1.6 11.2 ± 3.1 11.6 ± 2.4 0.9 (n.s.)
   After therapy n/a n/a 9.2 ± 1.8 10.0 ± 1.8 8.8 ± 1.4 9.9 ± 1.5 2.2 (n.s.)
  1. P: *<0.05, **<0.01, ***<0.001; Duncan test: †, sham/tPA > control/NBO/HBO/HBO+tPA; ‡, HBO+tPA < sham/control/HBO/tPA; §, sham < control/NBO/HBO/tPA/HBO+tPA; II, HBO+tPA > NBO/HBO/tPA