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Figure 3 | Experimental & Translational Stroke Medicine

Figure 3

From: The 1027th target candidate in stroke: Will NADPH oxidase hold up?

Figure 3

NOX4 deletion confers neuroprotection during stroke[12]. The upper images show the TTC staining of coronal brain slices after cerebral I/R in WT, NOX1-, NOX2- and NOX4 KO mice on 24 hours after tMCAO (1 hour ischemia). The infarct volume (white region) is about 75% smaller in NOX4 deficient mice compared to the other mice, as also illustrated by the bar graph. Stroke experiments were also performed in female mice and in older animals, obtaining the same results.

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