Figure 2

Edema formation and Stroke Outcomes (A). Absolute water content. (B). Relative water content. *P < 0.05 vs. the ipsilateral hemisphere in WT mice; **P < 0.05 vs. the ipsilateral hemisphere in each group. n = 6/per group. (C&D). Infarct volumes in the cortex, striatum, and whole hemisphere in both Verge KO and WT mice after 24 and 72 hours of MCAO. No significant differences were seen between KO and WT mice. (E). Box-and-whisker plot for NDS at 1.5 and 72 hours of MCAO. NDS was indicated as Median (interquartile range): KO 1.5 h, 3(3–4); WT 1.5 h, 3(3–3.5); KO 72 h, 2(1–2); WT 72 h, 2(1.5–2). *P < 0.05 vs. NDS of 1.5 h in each group. n = 7 ~ 9/per group