Figure 1From: Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo Mean percentage neuronal cell death. A. Data are shown for cells exposed to normal conditions (NC) or glucose deprivation with vehicle for 24 h (GD). Other cells exposed to GD were treated with CGP42112 at 1x10-8 M (CGP-8), 1x10-7 M (CGP-7), 1x10-6 M (CGP-6) (n = 8) (*P < 0.05 vs. NC). B. Data are shown for cells exposed to normal conditions (i.e. 24 h NC) or glucose deprivation with vehicle (24 h GD) or 3 concentrations of CGP42112 in the presence of PD123319 at 1x10-6 M (PD-6). Data for GD with PD123319 alone (n = 6) are also shown (*P < 0.05 vs. vehicle; NS P > 0.05 vs. vehicle). C. Data are shown for cells exposed to normal conditions (NC) or glucose deprivation (GD) with vehicle (24 h GD) or 1x10-6 M CGP42112 (CGP-6) in the absence or presence of 1x10-7 M candesartan (CV-7) (n = 7; *P < 0.05 vs. vehicle).Back to article page