A-D. Development of functional deficits measured by ladder rung (A-B) and neurological severity score (mNSS; C-D). Experimental stroke caused a significant increase of ladder rung gait errors (A) and mNSS scores (C) at day 2. Gait errors decreased to a plateau during the remaining experiment, while the animals did not show any recovery of mNSS scores. The area under the curve (AUC) analyses (B and D) did not show any statistically significant differences between the experimental groups. Values are means ± SD for 7 samples per group.