Brain water content (BWC) 3 hours following SAH or in respective control animals. Streaked gray area indicates the range of normal brain water content in animals not subjected to long-term anesthesia. BWC is within the normal range under MMF anesthesia while it is elevated in rats anesthetized with isoflurane (p < 0.05) or chloral hydrate (Control). Following SAH BWC increased only in animals anesthetized with isoflurane while it remained unchanged in animals receiving chloral hydrate or MMF. Values are presented as mean ± SEM for n = 5 in each group, *p < 0.05 vs. isoflurane (Kruskal-Wallis ANOVA on ranks followed by Dunn's Method).