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Table 1 Physiological parameters during surgical preparation, before, and after SAH

From: Impact of anesthesia on pathophysiology and mortality following subarachnoid hemorrhage in rats

    physiological conditions after SAH
   Preparation 0 min 60 min 180 min 0 min 60 min 180 min
Ventilation rate (v/min) chloral hydrate 36 ± 1 36 ± 2 46 ± 3* 47 ± 3* 37 ± 1 39 ± 2 42 ± 4*
  isoflurane 35 ± 2 44 ± 4* 51 ± 2* 58 ± 2* 44 ± 2 43 ± 2 47 ± 3*
  MMF 32 ± 2 30 ± 2 29 ± 2 27 ± 1 35 ± 3 35 ± 4 34 ± 3
Art. pCO2 (mmHg) chloral hydrate 36.9 ± 2.9 41.6 ± 2.8 41.8 ± 2.5 40.8 ± 3.4 40.5 ± 1.7 41.7 ± 2.2 43.2 ± 3.0
  isoflurane 44.2 ± 1.9 45.1 ± 3.1 41.7 ± 4.0 42.9 ± 2.7 38.6 ± 0.8 44.1 ± 2.0 42.4 ± 2.9
  MMF 40.3 ± 3.1 37.1 ± 1.2 34.5 ± 2.4 37.8 ± 3.3 41.7 ± 0.6 44.3 ± 2.3 43.3 ± 3.1
Art. pO2 (mmHg) chloral hydrate 136.6 ± 4.1 120.3 ± 3.4 116.0 ± 6.3# 113.1 ± 4.7# 125.1 ± 6.8# 116.5 ± 7.1# 109.6 ± 9.4
  isoflurane 121.1 ± 4.2 105.1 ± 7.8 89.6 ± 2.8 86.4 ± 3.9 99.8 ± 5.3 92.3 ± 3.1 90.1 ± 5.6
  MMF 125.6 ± 9.5 122.2 ± 9.7 135.6 ± 8.8# 135.4 ± 6.7# 105.2 ± 8.0 106.2 ± 6.9# 116.1 ± 9.5
pH chloral hydrate 7.29 ± 0.03 7.30 ± 0.02 7.29 ± 0.02 7.28 ± 0.03 7,34 ± 0,02 7.33 ± 0.01 7,28 ± 0,02
  isoflurane 7.29 ± 0.02 7.32 ± 0.05 7.33 ± 0.04 7.35 ± 0.03 7,33 ± 0,01 7.29 ± 0.01 7,31 ± 0,03
  MMF 7.34 ± 0.07 7.37 ± 0.01 7.35 ± 0.02 7.35 ± 0.01 7,37 ± 0,02 7.34 ± 0.04 7,35 ± 0,01
Glucose (mg/dl) chloral hydrate 196 ± 24 231 ± 20 169 ± 14 115 ± 16 186 ± 27 162 ± 23 138 ± 18
  isoflurane 165 ± 20 158 ± 20 120 ± 10 114 ± 6 131 ± 15 121 ± 9 128 ± 8
  MMF 196 ± 51 191 ± 37 156 ± 23 174 ± 26 208 ± 43 173 ± 17 181 ± 24
Lactate ( mmol/l) chloral hydrate 1.0 ± 0.1 1.1 ± 0.1 0.8 ± 0.1 0.6 ± 0.1 1.2 ± 0.3 1.4 ± 0.3 0.7 ± 0.1
  isoflurane 1.0 ± 0.1 1.3 ± 0.1 1.4 ± 0.2 1.5 ± 0.3 1.2 ± 0.3 0.8 ± 0.1 1.0 ± 0.0
  MMF 0.5 ± 0.1 0.6 ± 0.0 0.7 ± 0.1 0.8 ± 0.2 0.6 ± 0.0 1.1 ± 0.1 0.8 ± 0.2