Figure 5

Correlation matrix between changes (∆) in body weight, functional impairment and blood–brain barrier (BBB) impairment in the overall sample (color-coded in yellow) and the control group (color-coded in turquoise). Functional impairment was assessed according to Menzies et al. [27]; BBB impairment was measured as previously described by Michalski et al. [41, 44]; sample sizes for calculations in the overall sample: ranging from n = 23 to n = 38, and for calculations in controls: ranging from n = 8 to n = 11.