Figure 2

a-d 24-h ambulatory blood pressure profiles in colorectal cancer patients in response to bevacizumab infusion. Diastolic blood pressure during daytime but not during nighttime decreased after bevacizumab infusion (Figure 2 a,b). The proportion of individuals with pathological blood pressure profile increased after bevacizumab (Figure 2 c,d). Legend: systolic blood pressure (broken lines), diastolic blood pressure (smooth lines); proportions are based on the diagnostic criteria of the European Society of Hypertension and the American Hypertension Association before (day-1), during (day 0) and after (day+1) bevacizumab infusion.