Table 1 Identified phase III studies
Study acronym/study title | Year of publication | Intervention | No. of subjects | Result |
|---|---|---|---|---|
PAIS | 2009 | Acetaminophen | 1400 | Neutral |
AHAIS | 2001 | Aptiganel | 628 | Neutral |
BEST | 1988 | Atenolol, Propanolol | 302 | Neutral |
POST-010 and POST-011 | * | BMS-204352 | 1978 | Neutral |
SCAST | 2011 | Candesartan | 2004 | Neutral |
Cervene phase 3 | 2000 | Cervene (Nalmefene) | 368 | Neutral |
Citicoline ECCO 2000 | 2001 | Citicoline | 899 | Neutral |
Citicoline 007 | 1999 | Citicoline | 394 | Neutral |
ICTUS | 2012 | Citicoline | 2298 | Neutral |
CLASS | 1999 | Clomethiazole | 1360 | Neutral |
CLASS-I | 2002 | Clomethiazole | 1198 | Neutral |
EGASIS | 2006 | Diazepam | 880 | Neutral |
MACSI | 2013 | DP-b99 | 446 | Neutral |
EAIS | 1998 | Ebselen | 302 | Neutral |
EAST | 2009 | Edaravone | 814 | Neutral |
Eliprodil phase III | * | Eliprodil | 483 | Neutral |
EAST | 2001 | Enlimomab | 625 | negative |
ESS | 2009 | Epoetin Alfa | 522 | Neutral |
Fiblast phase III | 2002 | Fibroblast growth factor | 286 | Neutral |
FIST | 1996 | Flunarizine | 331 | Neutral |
Fosphenytoin phase III | * | Fosphenytoin | 462 | Neutral |
GAIN International | 2000 | Gavestinel (GV150526) | 1804 | Neutral |
GAIN Americas | 2001 | Gavestinel (GV150526) | 1367 | Neutral |
EST | 1994 | GM1 ganglioside | 792 | Neutral |
SASS | 1994 | GM1 ganglioside | 287 | Neutral |
IASSH | 1989 | GM1 ganglioside | 502 | Neutral |
ASCLEPIOS | 1994 | Israpidine | 357 | Neutral |
LUB-INT-13 | 2000 | Lubeluzole | 1786 | Neutral |
Lub | 1997 | Lubeluzole | 721 | Neutral |
IMAGES | 2004 | Magnesium | 2589 | Neutral |
PRISTINE | 1996 | Naftidrofuryl | 620 | Neutral |
ANS | 1992 | Nimodipine | 1064 | Neutral |
INWEST | 1994 | Nimodipine | 295 | negative |
TRUST | 1990 | Nimodipine | 1215 | Neutral |
VENUS | 2001 | Nimodipine | 454 | Neutral |
SAINT II | 2007 | NXY-059 | 3306 | Neutral |
SAINT I | 2006 | NXY-059 | 1722 | positive |
RREACT | 2007 | ONO-2506, Arundic acid | 841 | Neutral |
PASS | 1997 | Piracetam | 927 | Neutral |
mRECT | 2009 | Repinotan | 681 | Neutral |
ASSIST | 2000 | Selfotel (CGS19755) | 567 | Neutral |
RANTTAS | 1996 | Tirilazad mesylate | 556 | Neutral |
RANTTAS II | 1998 | Tirilazad mesylate | 126 | Neutral |
NEST-2 | 2009 | Transcranial laser therapy | 660 | Neutral |
ASTIN | 2003 | UK279,276 | 966 | Neutral |
ARTIST+ | * | YM872 | 312 | Neutral |