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Figure 3 | Experimental & Translational Stroke Medicine

Figure 3

From: Development and characterization of a Yucatan miniature biomedical pig permanent middle cerebral artery occlusion stroke model

Figure 3

Ischemic injury results in cerebral atrophy and aberrant brain remodeling. T2-weighted transverse (A & D), dorsal plane DWI (B), dorsal ADC maps (C & F) and T2w-FLAIR (E) are shown from a pig with MR characteristics of a stroke at 24 hrs (A-C) and 90 days post (D-F). At 24 hrs post-lesion, abnormal cerebral territorial hyperintense lesions were identified in 7 pigs in the T2w (A) and DWI (B) images, with territorial regions of restricted diffusion on the ADC maps (C). At 90 days, marked cerebral cortical atrophy was present, with CSF filled cavities remaining at the prior site of infarction, consistent with hydrocephalus ex vacuo (D-F).

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