Laser Doppler flowmetry and infarction following middle cerebral artery occlusion with platelet rich clots (Study 1). A total of seven rats had successful embolization of the MCA. (A) Five rats remained occluded for the duration of LDF observation (mean ± SD). One rat died overnight and was not included in TTC assessment of infarct. (B) Two rats recanalized at 40 min (black trace) and 70 min (grey trace) (raw data).