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Fig. 2 | Experimental & Translational Stroke Medicine

Fig. 2

From: Artery reopening is required for the neurorestorative effects of angiotensin modulation after experimental stroke

Fig. 2

Reperfusion modulates the ability of candesartan to affect the expression of BDNF/TrkB system components. Candesartan increased mature BDNF expression in the contralateral hemisphere in a reperfusion dependent manner (A). The effect of reperfusion is most prominent in proBDNF (B), BDNF/proBDNF ratio (C), and TrkB (D) expression. Groups connected by line are significantly different from each other. a,b pairs of means with different letters are significantly different from each other. n = 4 per group

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