Figure 1From: Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studiesG-CSF reduces infarct sizes and enhances functional recovery in stroke models by several mechanisms of action, such as the induction of anti-apoptotic pathways, neurogenesis and angiogenesis. Thereby G-CSF acts as a direct protectant for neurons expressing its receptor. G-CSF's influences on immunocompetence and inflammation parameters are potential additional effects.Back to article page