Figure 1From: Attenuation of circulatory shock and cerebral ischemia injury in heat stroke by combination treatment with dexamethasone and hydroxyethyl starch Physiological parameters, and cellular ischemia and injury markers. Effects of heat exposure (ambient temperature; Ta = 42°C for 80 min) on colonic temperature (Tco), mean arterial pressure (MAP), heart rate (HR), cerebral blood flow (CBF) and the extracellular concentrations of glutamate, glycerol, and lactate/pyruvate ratio of the corpus striatum in normothermic control rats (open circles), 0.9% NaCl solution (11 ml/kg)-treated (filled circles), DXM (4 mg/kg)-treated (open squares), HES (10%, 11 ml/kg)-treated (filled squares), or the combined agent (DXM+HES)-treated rats (open triangles). The dotted line indicates time of heat stroke onset and drug injection. *P < 0.05, compared with normothermic control rats. †P < 0.05, compared with saline-treated rats (Ta = 42°C for 80 min).# P < 0.05, compared with HES-treated rats (Ta = 42°C for 80 min) (ANOVA followed by Duncan's test).Back to article page