Figure 1
From: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9)
Whole cell currents recorded from relay neurons in thalamic slice preparations show characteristics indicative for K 2P 9.1 channels. (A) Mean ramp currents under control recording conditions (ctrl) and after removal of extracellular divalent cations (div. cation free). Inset: Currents were evoked by ramping the membrane potential from -35 mV to -125 mV over 800 ms. (B) I-V relationship of the divalent cation-sensitive current component shows characteristics indicative of TASK channels. I = current; ISO = standing outward current; VM = membrane potential.