Figure 10From: Safety evaluation of a recombinant plasmin derivative lacking kringles 2-5 and rt-PA in a rat model of transient ischemic stroke Temporal progression of the infarct volume. Rats were exposed to the designated duration of MCAo. All rats were euthanized 24 hours after MCAo onset to allow the infarct to mature. Statistics: Groups with like letters are not significantly different (p < 0.05; ANOVA, Tukey-Kramer HSD). Group values are the mean ± SEM.Back to article page