Figure 4From: Safety evaluation of a recombinant plasmin derivative lacking kringles 2-5 and rt-PA in a rat model of transient ischemic stroke Clot lysis kinetics of Δ(K2-K5) plasmin. Retracted whole blood clots (87 mg) from humans, canines and rats were exposed to 1.14 mg/mL Δ(K2-K5) plasmin in vitro. At the indicated time points, samples were assayed for optical density at 280 nm.Back to article page