Immunofluorescent localization of IL-10 in Wistar rat brains after tMCAO. IL-10 strongly co-localized with NeuN in the ischemic penumbra and contralesional cortical, striatal and hippocampal neurons with less expression in the ischemic core neurons or activated microglia (CD68). IL-10 showed no co-localiztion with markers of astrocytes (GFAP) or endothelial cells (VWF). Images were taken from 24 h brain sections. 72 h brain sections showed similar pattern. N = 4 per group.