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Figure 4 | Experimental & Translational Stroke Medicine

Figure 4

From: Early microvascular dysfunction in cerebral small vessel disease is not detectable on 3.0 Tesla magnetic resonance imaging: a longitudinal study in spontaneously hypertensive stroke-prone rats

Figure 4

No pathology on magnetic resonance imaging in spontaneously hypertensive stroke-prone rats (SHRSP) with only stases. T1-weighted (T1w; A), T2-weighted (T2w; B), T2 constructive interference in steady state (C) and T2 gradient echo (D) (A–D: DfB −3.2 mm) sequences with coronal slice orientation performed at the age of 34 weeks in SHRSP K2R3 showed no abnormal findings. Histology at the age of 34 weeks displayed arteriolar stases in the cortex (E) and capillary stases in the hippocampus (F). w – age in weeks; DfB – distance from bregma. Scale bar in E and F: 50 μm.

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