Table 1 Study design for the experiment I (without IV-tPA; 1a), and experiment II (with IV-tPA; 1b)
a, Experiment I: Without IV-tPA post-stroke | ||
|---|---|---|
No MINO (IV-Saline 1 hr post-stroke) | Yes MINO (IV-MINO 1 hrs post-stroke) | |
No RIPerC (RIPerC Sham at 2 hrs post-stroke) | Saline, RIPerC Sham (+Veh+Sham Group) | MINO, RIPerC Sham (+MINO Group) |
Yes RIPerC (RIPerC Therapy at 2 hrs post-stroke) | Saline, RIPerC Therapy (+Veh+RIPerC Group) | MINO, RIPerC Therapy (+MINO+RIPerC Group) |
b, Experiment II: With IV-tPA (or vehicle) at 4 hrs post-stroke | ||
No MINO (IV-Saline 1 hr post-stroke) | Yes MINO (IV-MINO 1 hrs post-stroke) | |
No RIPerC (RIPerC Sham at 2 hrs post-stroke) | Saline, RIPerC Sham (+Veh+Sham Group) | MINO, RIPerC Sham (+MINO Group) |
Yes RIPerC (RIPerC Therapy at 2 hrs post-stroke) | Saline, RIPerC Therapy (+Veh+RIPerC Group) | MINO, RIPerC Therapy (+MINO+RIPerC Group) |