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Table 1 Methods for the assessment of collateral blood flow in experimental stroke models

From: Cerebral collateral circulation in experimental ischemic stroke

Method Temporal resolution Spatial resolution CBF information Invasiveness Cost
MRI Not real-time Whole brain with low resolution Perfusion maps None High
LSCI Almost real-time Strictly surface reading Relative CBF values Craniotomy may be necessary Moderate
TPLSM Repetitive scanning required Depth resolution Quantitive CBF velocity and direction in single vessels Craniotomy necessary High
LDF (multi-site) Real-time monitoring Integrated reading in 1 mm3 cortical volume Relative CBF values Craniotomy not necessary Moderate