Table 1 Methods for the assessment of collateral blood flow in experimental stroke models
From: Cerebral collateral circulation in experimental ischemic stroke
Method | Temporal resolution | Spatial resolution | CBF information | Invasiveness | Cost |
|---|---|---|---|---|---|
MRI | Not real-time | Whole brain with low resolution | Perfusion maps | None | High |
LSCI | Almost real-time | Strictly surface reading | Relative CBF values | Craniotomy may be necessary | Moderate |
TPLSM | Repetitive scanning required | Depth resolution | Quantitive CBF velocity and direction in single vessels | Craniotomy necessary | High |
LDF (multi-site) | Real-time monitoring | Integrated reading in 1 mm3 cortical volume | Relative CBF values | Craniotomy not necessary | Moderate |